PROGNOSIS BIOTECH HISTAMINE KITS
Scombrotoxin fish poisoning is caused by ingestion of certain species of fish that contain high levels of histamine. Tuna, mahi-mahi, mackerel, herring, marlin, and bluefish are the fish most associated with histamine formation when a time/ temperature abuse results in bacterial release of histidine decarboxylase and subsequent reaction with the amino acid, histidine, to produce histamine. FDA provides a guidance level of 50 ppm maximum histamine in the edible portion of fish. Levels of 50 ppm or more histamine is indicative of decomposition in these fish, whether or not organoleptic examination detects decomposition. Health Canada has established a maximum limit of 100 ppm in most fish and fish products, and 200 ppm for anchovies, fermented fish sauces and pastes. Histamine is heat-stable, which makes it a useful indicator of prior decomposition, even in thermally processed fish.
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